Active Outline

General Information

Course ID (CB01A and CB01B)
CHEMD030B
Course Title (CB02)
Introduction to General, Organic and Biochemistry II
Course Credit Status
Credit - Degree Applicable
Effective Term
Fall 2024
Course Description
This course is the second quarter of the general inorganic, organic, and biological chemistry course for students entering allied health fields. Introduction to General, Organic, and Biochemistry II focuses on organic chemistry and biochemistry. Topics covered include organic structure, nomenclature, physical properties, and reactivity of small organic molecules. Functional groups will be introduced in the context of their reactivity and biochemical roles. Additional biochemistry topics surveyed include biological macromolecules (carbohydrates, fatty acids and lipids, amino acids and proteins, nucleic acids and DNA) as well as metabolism and enzymatic reactions. The physical and chemical properties of these biological molecules will be examined.
Faculty Requirements
Discipline 1
[Chemistry]
FSA
[FHDA FSA - CHEMISTRY]
Course Family
Not Applicable

Course Justification

This course is transferable to CSU and UC. This course is De Anza GE, CSU GE, and IGETC, and also on the Medical Laboratory Technology A.A. degree. This is the second course in the two-part sequence of introduction to chemistry, specifically organic and biological, for students entering allied health fields.

Foothill Equivalency

Does the course have a Foothill equivalent?
Yes
Foothill Course ID
CHEM F030B

Course Philosophy

Formerly Statement

Course Development Options

Basic Skill Status (CB08)
Course is not a basic skills course.
Grade Options
  • Letter Grade
  • Pass/No Pass
Repeat Limit
0

Transferability & Gen. Ed. Options

Transferability
Transferable to both UC and CSU
CSU GEArea(s)StatusDetails
CGB1CSU GE Area B1 - Physical ScienceApproved
CGB3CSU GE Area B3 - Science Laboratory ActivityApproved
IGETCArea(s)StatusDetails
IG5AIGETC Area 5A - Physical ScienceApproved
IG5CIGETC Area 5C - Science LaboratoryApproved

Units and Hours

Summary

Minimum Credit Units
5.0
Maximum Credit Units
5.0

Weekly Student Hours

TypeIn ClassOut of Class
Lecture Hours4.08.0
Laboratory Hours3.00.0

Course Student Hours

Course Duration (Weeks)
12.0
Hours per unit divisor
36.0
Course In-Class (Contact) Hours
Lecture
48.0
Laboratory
36.0
Total
84.0
Course Out-of-Class Hours
Lecture
96.0
Laboratory
0.0
NA
0.0
Total
96.0

Prerequisite(s)

CHEM D001A, CHEM D01AH, CHEM D025. or CHEM D030A

Corequisite(s)

Advisory(ies)

ESL D272. and ESL D273., or ESL D472. and ESL D473., or eligibility for EWRT D001A or EWRT D01AH or ESL D005.

Limitation(s) on Enrollment

Entrance Skill(s)

General Course Statement(s)

(See general education pages for the requirements this course meets.)

Methods of Instruction

Lecture and visual aids

Discussion of assigned reading

Class discussion and problem solving

Quiz and examination review

Homework and extended projects

Laboratory experience which involves students in formal exercises of data collection and analysis

Laboratory discussion sessions and quizzes that evaluate the preceding weekly laboratory exercises

Assignments

  1. Reading
    1. Required readings from the textbook or other primary sources in preparation for the scheduled lecture. This may include entire chapters or sections from the chapters covering topics included in this outline.
    2. Required readings from the laboratory manual as a preparation for the scheduled experiment in order to provide students with familiarity with the specific laboratory protocols and related safety precautions necessary for the successful completion of the experiment.
  2. Writing
    1. Homework assignments based on classroom discussion/lecture may include answering questions from end-of-chapter exercises or other sources as deemed appropriate by the instructor.
    2. Periodic quizzes and mid-term examinations based on material discussed in lectures and/or reading assignments
  3. Laboratory Assignments
    1. Pre-lab exercise: The pre-lab assignment for the scheduled laboratory experiment to be completed when beginning a new experiment. This assignment may be identical to that provided in the laboratory manual or substituted with other appropriate assignments determined by the instructor.
    2. Report-sheet: Data obtained in laboratory exercises are to be entered in the assigned laboratory manual or a laboratory notebook. Analysis of data and results will be evaluated for accuracy and comprehension.

Methods of Evaluation

  1. Homework assignments based on end-of-chapter problems from the primary text may be evaluated for completion to test comprehension of lectures and assigned reading.
  2. Mid-term examinations and/or periodic quizzes will be used to evaluate the ability of students to a) solve problems, b) outline various concepts covered in the lecture, and c) demonstrate an understanding of reading assignments. These will be evaluated for accuracy to assess student progress in achieving various learning outcomes.
  3. A comprehensive final examination or project in any chosen format (multiple choice questions or free response) will be based on the course material covered during the entire quarter and evaluated for accuracy.
  4. Pre-lab assignments will be evaluated for completeness and level of preparedness required for the safe and timely execution of laboratory protocols and experiments.
  5. Report sheets and/or laboratory reports will be evaluated for the successful completion of laboratory experiments as well as the accuracy of data analysis and interpretation.
  6. A comprehensive laboratory examination or project may be used to evaluate the student's understanding of the various concepts discussed in the different experiments performed during the course. Concepts evaluated may include: a) general laboratory protocol b) comprehension of data analysis and interpretation and c) critical thinking as it pertains to the scientific method.

Essential Student Materials/Essential College Facilities

Essential Student Materials: 
  • Chemistry department approved safety goggles
  • Nitrile or latex gloves
Essential College Facilities:
  • Classroom with chart of "Periodic table of elements"
  • Lab facility with sufficient fume hoods

Examples of Primary Texts and References

AuthorTitlePublisherDate/EditionISBN
Smith, Janice GGeneral, Organic, and Biological ChemistryMcGraw-Hill2022/5th edition9781264876174
Applegate, Neely, and SakutaLaboratory Manual for General, Organic, and Biological ChemistryMcGraw Hill2016/1st edition978-0-073-51125-2
TimberlakeAn Introduction to General, Organic, and Biological ChemistryPearson2017/13th edition978-0-134-42135-3
Ball, Hill, and ScottThe Basics of General, Organic, and Biological ChemistryLibretext2022
Krieger, Paul AA Visual Analogy Guide to ChemistryMorton2012

Examples of Supporting Texts and References

None.

Learning Outcomes and Objectives

Course Objectives

  • Examine the chemistry of simple organic molecules with an emphasis on structural features and nomenclature
  • Discuss contributions by scientists to the fields of organic chemistry, biochemistry, and chemical biology.
  • Identify stereochemical centers and differentiate enantiomers from other stereo- and geometric isomers.
  • Examine the structure, reactivity and nomenclature of hydrocarbons.
  • Analyze and assess the properties of alcohols, thiols, ethers, aldehydes and ketones, carboxylic acids, esters, amines, and amides in the context of biological activity and applications
  • Examine the structure, stereochemistry, and reactivity of carbohydrates
  • Examine structure and chemistry of fatty acids and lipids, as well as applications to the architecture of the cell membrane
  • Examine the structure and chemistry of amino acids and proteins
  • Examine the structure and chemistry of nucleic acids and apply these principles to the process of protein synthesis
  • Apply principles of organic structure and reactivity to metabolic pathways

CSLOs

  • Differentiate the general reactions of the principle organic functional groups.

  • Evaluate the major classes of biological compounds from a chemical perspective.

Outline

  1. Examine the chemistry of simple organic molecules with an emphasis on structural features and nomenclature
    1. Introduction to organic chemistry
    2. Introduction to IUPAC nomenclature rules for organic compounds
    3. Introduction to functional groups
  2. Discuss contributions by scientists to the fields of organic chemistry, biochemistry, and chemical biology.
    1. Highlight scientists that contributed to the historical development of organic chemistry and biochemistry.
    2. Feature contemporary scientists and their research contributions.
  3. Identify stereochemical centers and differentiate enantiomers from other stereo- and geometric isomers.
    1. Cis-trans geometric isomers
    2. Introduction to chiral molecules
    3. Optical activity
  4. Examine the structure, reactivity and nomenclature of hydrocarbons.
    1. Linear, branched, and cyclic alkanes
    2. Conformers
    3. Alkenes and alkynes
    4. Addition reactions
    5. Polymers of alkenes
    6. Aromatic compounds
    7. Physical properties of hydrocarbons: intermolecular forces, solubility, and boiling points
  5. Analyze and assess the properties of alcohols, thiols, ethers, aldehydes and ketones, carboxylic acids, esters, amines, and amides in the context of biological activity and applications
    1. Structural features and nomenclature
    2. Physical properties including solubility, hydrogen-bonding and boiling points
    3. Reactions of alcohols and thiols: dehydration, oxidation, and reduction
    4. Benedict's test and Tollen's test for aldehydes and ketones
    5. Hydrolysis and neutralization of carboxylic acids
    6. Hydrolysis and saponification of esters
    7. Amines as a Bronsted-Lowry base and related acid-base chemistry
    8. Reactions of amides: acid and base hydrolysis, enzymatic digestion
  6. Examine the structure, stereochemistry, and reactivity of carbohydrates
    1. Monosaccharides, aldoses, and ketoses
    2. Stereochemistry of monosaccharides: Fischer projections and Haworth structures
    3. Chemical properties of monosaccharides
    4. Disaccharides: lactose, maltose, and sucrose
    5. Polysaccharides: amylose, amylopectin, glycogen, and cellulose
    6. Stereochemistry of carbohydrates
    7. Biological applications of carbohydrate chemistry such as cell-surface chemistry
  7. Examine structure and chemistry of fatty acids and lipids, as well as applications to the architecture of the cell membrane
    1. Structural features of lipids and fatty acids
    2. Melting points of fatty acids and applications to nutrition
    3. Structural features of triacylglycerols
    4. Chemical properties of triacylglycerols
    5. Glycerophospholipids
    6. Steroids, cholesterol, and steroid hormones
    7. Cell membranes
  8. Examine the structure and chemistry of amino acids and proteins
    1. Functions of proteins and enzymes
    2. Structure and functionality of amino acid sidechains
    3. Acid-base properties of amino acids and the Zwitterionic form
    4. Formation of peptides through amide coupling and translation
    5. Primary, secondary, and tertiary protein structure
    6. Enzymes and enzyme action
    7. Factors affecting enzyme activity
    8. Enzyme cofactors
    9. Stereochemistry of amino acids
  9. Examine the structure and chemistry of nucleic acids and apply these principles to the process of protein synthesis
    1. Nucleotides and nucleosides
    2. Primary structure of nucleic acids
    3. DNA double helix
    4. RNA and the genetic code
    5. Protein synthesis
    6. Genetic mutations
  10. Apply principles of organic structure and reactivity to metabolic pathways
    1. ATP as the energy currency of the cell
    2. Outline the chemical steps of glycolysis, the citric acid cycle, and oxidative phosphorylation
    3. Introduce additional metabolic and catabolic pathways such as amino acid catabolism

Lab Topics

  1. Laboratory Methodology
    1. Maintaining a record of laboratory activities and data
    2. Communicating and reporting results
  2. Chemical Safety
    1. Safety Data Sheets (SDSs)
      1. Evaluating SDSs for hazards and protective measures
      2. Using the globally harmonized system (GHS) pictograms to assess and manage risks in the lab
    2. Chemical disposal
      1. Separation of waste streams based on compatibility and reactivity.
      2. Proper disposal methods of organic materials
      3. Environmental hazards of improper waste disposal
    3. Laboratory Environment
      1. Maintaining laboratory cleanliness
      2. Labeling chemical containers and chemical reactions
      3. Segregation of chemicals by hazard
      4. Secondary containment to limit release of hazardous materials
    4. Personal Safety
      1. The importance of correct personal protective equipment such as safety goggles, gloves, and lab coats
      2. Strategies to limit chemical exposure
      3. Safety shower location and use
      4. Eyewash station location and use
      5. Location of fire extinguishers
    5. Emergency Situations
      1. Fires
      2. Earthquakes
      3. Chemical spills and chemical exposure
      4. Location of the nearest AED
      5. Evacuation procedures
  3. Laboratory Techniques
    1. Use of micropipettes
    2. Use of an analytical balance (e.g. taring and mass by difference)
    3. Spectroscopic analysis of organic functional groups
  4. Reactivity of Small Organic Molecules
    1. Reactions of hydrocarbons such as halogenation and oxidation
    2. Synthesis and characterization of small organic molecules
  5. Chemical properties of biological macromolecules
    1. Application of molecular biology techniques to the study of macromolecular nucleic acids and proteins.
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